PRELIMINARY EXPERIENCE WITH ICI 35 868 AS AN I.V. INDUCTION AGENT: COMPARISON WITH ALTHESIN
نویسندگان
چکیده
منابع مشابه
Animal studies of the anaesthetic activity of ICI 35 868.
The activity of a new i.v. anesthetic agent ICI 35 868, a compound unrelated to currently used barbiturate, eugenol or steroid agents, has been examined in a range of animal species. Some of the properties of ICI 35 868 resemble those of thiopentone in that it is a rapidly acting agent which produces anaesthesia of short duration and without excitatory side-effects. Both agents have a similar t...
متن کاملBritish Journal of Anaesthesia Leeds Dosage of Ici 35 868
McCubbin, T. D., Brown, J. H., Dewar, K. M. S., Jones, C. J., and Spence, A. A. (1979). Glycopyrrolate as a premedicant: comparison with atropine. Br. J. Anaesth., 51, 885. Rupreht, J. (1980). Physostigmine rcversaj of diazepam. Anesthesiology, (in press). Dworacek, B. (1976). Central anticholinergic syndrome in anaesthetic practice. Acta Anaesthesiol. Belg., 27, 45. Selenati, A. (1979). Recett...
متن کاملPharmacokinetics in laboratory animals of ICI 35 868, a new i.v. anaesthetic agent.
Blood concentrations of ICI 35 868 have been determined in rat, pig, rabbit and cat after single i.v. injections. In all species the initial distribution volume was greater than blood volume and the overall distribution volume was large. Half-lives of the distribution phase were extremely short (1-6 min) and the terminal half-lives were also short (16-55 min). In all species examined a correlat...
متن کاملA study of three doses of ici 35 868 for induction and maintenance of anaesthesia.
Three doses (1.5, 2.0 and 2.5 mg kg-1) of diisopropyl phenol (ICI 35 868) were compared for induction and maintenance of anaesthesia in healthy females undergoing short gynaecological procedures. Induction of anaesthesia was smooth and rapid. Cardiovascular changes (which were dose-dependent) included a decrease in arterial pressure and an increase in heart rate. These changes were magnitudes c...
متن کاملAlthesin as an induction agent for Caesarean section.
Thirty patients for elective lower segment Caesarean section were randomly divided into two groups. One group received 50 mulitre/kg of Althesin for induction of anaesthesia and the other, 100 mulitre/kg. The two maternal groups were similar. There was no significant difference in the clinical or biochemical status of the infants except that infants in the low dose group had a significantly hig...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1980
ISSN: 0007-0912
DOI: 10.1093/bja/52.8.807